Do you use directing groups in catalysis and struggle to remove them at the end of a synthesis? Liam has utilised the time out of the lab during lockdown to bring you this review on how to remove 8-aminoquinoline, one of the most popular N,N-bidentate directing groups used in C–H activation and alkene functionalisation. We hope to provide a useful end-users’ guide for chemists in academia and industry who are considering using this powerful directing group—and want to be able to remove it from their final products.

For a link to the paper, click here: https://doi.org/10.1002/chem.202100093