Methods for selective deuterium incorporation into drug-like molecules have become extremely valuable due to the commercial, mechanistic, and biological importance of deuterated compounds. Today, we report a programmable, non-directed labelling platform for the C2, C3, or C2-and-C3 deuteration of indoles under mild, user-friendly conditions. Congratulations to Liam, who drove the project through the pandemic, as well as Rachael and Andrew.

Click here for a link to the paper in JOC.
A pre-print of this work was deposited in ChemRxiv in July 2022.